Zomato founder Deepinder Goyal has introduced the team of researchers behind Temple’s BrainFlow, a wearable system designed to continuously measure blood flow to the brain. The team includes Dr Divya Gulati and Dr Sanchit Gupta from the Indian Institute of Science (IISc), Dr Yukti Chopra from SISSA Trieste in Italy and Nitish Kumar from IIT Bombay. Goyal said the researchers led the development, construction and validation of the technology.
The researchers have expertise across systems neuroscience, neuroimaging, computational cognitive neuroscience, brain-computer interfaces and cerebral blood-flow research. Goyal said India has traditionally celebrated actors, cricketers and, more recently, entrepreneurs and startup founders, while arguing that scientists involved in such research also deserve greater recognition. He highlighted the team’s work in developing a system intended to monitor cerebral blood flow continuously through a wearable device.
BrainFlow is designed to address limitations associated with conventional methods of measuring blood flow to the brain. Goyal said the brain receives around 20 per cent of the body's blood supply and that cerebral blood flow changes with age. He argued that continuously monitoring these changes outside specialised medical environments has historically been difficult, with even hospital-based assessments often providing only a snapshot rather than continuous measurements.
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Temple has also conducted a validation study to examine whether BrainFlow measures changes associated with blood flow in the brain rather than only detecting changes in superficial tissues such as the scalp. According to Goyal, the company compared BrainFlow readings with time-domain near-infrared spectroscopy (TD-NIRS), a neuroimaging technique that can help distinguish cerebral tissue signals from superficial tissue signals. The reported validation study involved 60 participants, although complete findings have not been publicly detailed.
BrainFlow forms part of Temple’s broader focus on health and longevity. Goyal has described the company’s work as targeting factors that could contribute to extending healthy human life, with cerebral blood flow being one area of interest. Continuous measurements could potentially provide researchers with information about how circulation to the brain changes over time and how those changes relate to ageing and other biological processes.
However, the potential health and longevity applications of continuous cerebral blood-flow monitoring will require further research and independent validation. The publicly shared information does not establish that BrainFlow can diagnose medical conditions or that monitoring cerebral blood flow itself extends lifespan. Goyal said he was proud of the researchers working on the project and indicated that Temple intends to continue developing technologies aimed at understanding biological processes linked to healthy ageing.